Gut bacteria chemical linked to Alzheimer's disease progression
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University of Wisconsin-Madison researchers Vaibhav Vemuganti, Jea Woo Kang, Barbara B. Bendlin, and Federico E. Rey published a study in Nature Communications showing that imidazole propionate, a gut bacteria byproduct from histidine breakdown, accelerates Alzheimer’s disease brain changes. Analyzing blood samples from nearly 1,200 older adults, scientists found elevated blood levels correlate with worse cognitive decline in humans and drive neurodegeneration in animal models.
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