Restoring a brain protein reverses signs of aging in mice
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A study led by Lige Leng of Xiamen University, published March 16, 2023 in PLOS Biology, found that levels of the protein Menin decline with age in neurons of the hypothalamus, contributing to inflammation, cognitive decline, weaker bones, and thinner skin in mice. Restoring Menin reversed several of these age-related changes, while separate treatment with the amino acid D-serine improved cognition, pointing to a possible new target for healthy aging research.
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