Awake Surgery That Quieted the Right Amygdala Cut Fear Bias and PTSD in One Patient
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In a Nature Communications case study, a man with drug-resistant epilepsy and severe PTSD had part of his right amygdala inactivated during awake surgery. Within 20 minutes he stopped reading ambiguous faces as fearful; two months later his PTSD score dropped below the diagnostic threshold. Though based on a single patient, the work offers unusual causal evidence that right-amygdala activity helps sustain threat-focused interpretation bias and PTSD symptoms.
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