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Cryo-EM study explains how statins may trigger muscle pain via calcium leak

ScienceDaily · 2026-10-20
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UBC and University of Wisconsin–Madison researchers used cryo-electron microscopy to show statins can bind the muscle protein RyR1 and hold its calcium channel open, causing steady calcium leakage that may damage tissue and explain pain, weakness, and rare severe breakdown that can threaten the kidneys; the work is in Nature Communications.

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Source: ScienceDaily · via ahirlevel.hu

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