Blocking brain T cells preserved memory in Alzheimer’s mice without reducing tau
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Washington University School of Medicine scientists used an antibody to block CXCR3, limiting T cells entering the brains of mice with Alzheimer’s-like tau buildup. After months of treatment, brain T cells fell by about half; mice kept roughly 40% more tissue in memory regions and did better on memory tests while tau levels stayed unchanged. Findings were published September 28 in Neuron.
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